医療技術科学専攻　生体防御学　教授　山田武司

プロフィール

担当科目

先端医療科学特論(専門共通)、生体防御学特論?生体防御学演習(専門科目)

研究紹介

最近の業績

• Yamada T, Arakawa Y. Enhancement of antitumor activity by epigenetic regulation of tumour-specific T cells. Impact, Oct; 2021(8):6-8, 2021
• Toriyama K, Kuwahara M, Kondoh H, Mikawa T, Takemori N, Konishi A., Yorozuya T, Yamada T, Soga T., Shiraishi A, and Yamashita M. T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses. Commun. Biol., July 24; 3(1):394, 2020
• Yamada T, Nabe S, Toriyama K, Suzuki J, Inoue K, Imai Y, Shiraishi A, Takenaka K, Yasukawa M, and Yamashita M. Histone H3K27 demethylase negatively controls the memory formation of Ag-stimulated CD8+ T cells. J. Immunol. Feb; 202(4):1088-1098, 2019.
• Nabe S, Yamada T, Suzuki J, Toriyama K, Yasuoka T, Kuwahara M, Shiraishi A, Takenaka K, Yasukawa M, and Yamashita M. Reinforce the antitumor activity of CD8+ T cells via glutamine restriction. Cancer Science, Dec.109:3737-3750, 2018.
• Suzuki J, Yamada T, Inoue K, Nabe S, Kuwahara M, Takemori N, Takemori A, Matsuda S, Kanoh M, Imai Y, Yasukawa M and Yamashita M. The tumor suppressor menin prevents effector CD8 T cell dysfunction via metabolic restriction by targeting mTOR activation. Nature Communications, Aug; 9: 3296, 2018.
• Yamada T, Kanoh M, Nabe S, Yasuoka T, Suzuki J, Matsumoto A, Kuwahara M, Maruyama S, Fujimoto T, Sakisuka R, Yasukawa M, and Yamashita M. Menin plays a critical role in the regulation of the antigen-specific CD8+ T cell response upon Listeria infection. J. Immunol. Nov;197(10):4079-4089, 2016.
• Yasuoka T, Kuwahara M, Yamada T, Maruyama S, Suzuki J, Taniguchi M, Yasukawa M, Yamashita M. The transcriptional repressor Gfi1 plays a critical role in the development of NKT1- and NKT2-type iNKT cells. Plos One, June; 11(6):e0157395, 2016.

詳細な業績はこちらに→ https://researchmap.jp/0685

お知らせ

大学院の受験を考えている皆さん、当研究室では免疫に興味を持ち、一緒にT細胞の免疫応答に関する研究を進めてくれる大学院生を募集しています。